The latest version of oral vitamin C supplementation is liposomal vitamin C,
Liposomal vitamin C bypasses many of the complications of traditional vitamin C or ascorbic acid, and, according to Dr. Levy, you can achieve far higher intracellular concentrations this way.
"I'm all in favor of people trying this," Hunninghake says. "I think it can be used as an adjunct to I.V. vitamin C. Most people are only going to do I.V. vitamin C once or twice a week. So by doing the liposomal vitamin C, they can easily do 6 grams of liposomal vitamin C orally without a bit of gastrointestinal distress."From Hunninghake's perspective, liposomal vitamin C may still be somewhat unproven, but is nonetheless quite safe.
There are also other forms of vitamin C on the market, such as buffered forms of sodium ascorbate. One example would be Ester-C. These buffered forms are also effective and do not cause the gastrointestinal distress associated with conventional ascorbic acid.
So far, I have recommended avoiding Ester-C, as I believe it's an oxidized form of vitamin C, which could do more harm than good. Dr. Hunninghake disagrees with my assessment, stating he's never seen any evidence indicating that Ester-C might be an oxidized form of vitamin C.
Based on Dr. Hunninghake's expertise in this area, I may reconsider my stance on Ester-C, although I still believe liposomal vitamin C has benefits that cannot be matched by buffered forms of vitamin C.